Collaborative Research Workshop – 29 May, 2018

Factors affecting the efficacy of antimicrobial treatment of SRS

Tuesday, 29 May, 2018, 09.00 to 16.30

  • Preliminary results of descriptive analysis
  • Confirmation of risk factors and hypotheses
  • Data sources for analysis
  • Definition of treatment success
  • Identification of next research priority
  • Research Platform update

Lunch and simultaneous translation will be provided

Location: Hotel Solace, Puerto Varas

Please confirm your attendance by Thursday, 24 May to Andrea Meriño CONECTA SPA

 andrea.merino@conectaspa.cl

Seven companies started integrating data with the Research Platform.

We are delighted to announce that a total of seven (7) companies have joined the Research Platform in the last two weeks.  We thank these companies for their early support and confidence.

  • Salmones Aysen,
  • Australis Seafoods, 
  • Blumar Seafoods
  • Ventisqueros
  • Camanchaca
  • Salmones Antartica,
  • Multiexport Foods.

We are having ongoing meetings with several other companies and hope to have more good news very soon.

Australis and Salmones Aysen start the ball rolling!!

What a great way to start this April visit! Australis Seafoods and Salmones Aysen have demonstrated their full support for the Research Platform by starting the data integration process. Both companies have shown great confidence and vision through their early participation in the industry Research Platform.

Ausvet were delighted to work with Marcela Galanti, Patricio Pena Rehbein and the Australis data team on Friday 13 April to upload retrospective company data and progress the automated data transfer arrangements. David Garrido and Salmones Aysen’s data manager, Pamela Orellana started this week well by finalising the first automated data transfer to the Research Platform.

 

 

Angus Cameron, Ausvet’s project leader, is pleased with the early response but knows it is just the beginning. “We are very optimistic about other companies coming on board this week. We’re really keen to give them early rewards by generating sophisticated health related company-level analyses through the Research Platform. The industry-wide analyses won’t be able to be presented until we have integrated data from more companies. We are working hard to get as many as possible as early as possible.”

Both Australis and Salmones Aysen have shown strong support for the Research Platform from the outset of the project and they have played an important role in launching this important industry resource.

The Research Platform ensures data confidentiality for each company but integrates the data to enable it to be used for industry-wide risk factor analysis into SRS and Caligus this year and other research priorities in the future.

Ausvet is back in town!!

Angus Cameron and Catriona Mackenzie have arrived back in Puerto Varas for another visit.  We will be looking forward to arranging further meetings with companies, freshwater hatcheries and other industry associates from Tuesday, 10 April to Tuesday, 24 April.

Please take advantage of our presence to help us to complete the risk factor research, build the Research Platform and bring concrete benefits to your company and the Chilean aquaculture industry.

What’s App and phone:

Angus Cameron: + 56 990723354

Catriona Mackenzie: +56 982558320

Project workshops engage companies and researchers

Ausvet held three one-day workshops in Puerto Varas on 19, 20 and 21 March, 2018 to engage companies in the risk factor analyses, give updates on the new Research Platform and direct future research priorities.

The workshops were attended by 30 company representatives, researchers, and other industry stakeholders. They represented the continuation of Ausvet’s inclusive approach to research. Participants are considered as research partners and jointly guide the methodological approach, data access, and particularly interpretation of research results.

Analysis of SIFA/INFA data and setting research priorities

Sernpesca’s SIFA and INFA databases hold a wealth of information that may yield new insights into risk factors for SRS and Caligus. Ausvet’s initial analyses were presented in Puerto Varas on Monday, 19th March.

The key advantages of the SIFA and INFA databases are that they contain data about the entire industry, and they are immediately available. Their usefulness for in-depth epidemiological analysis is limited because they contain little detailed information about important risk factors (compared to company databases), but they provide a useful first step in the collaborative process of validating Ausvet’s chosen research methodology, seeking contributions from industry and in setting future research priorities.

SaTScan cluster analysis for SRS in Atlantic Salmon

A series of analytical methodologies were presented and discussed in detail, including descriptive visualisations of the data, spatial and temporal clustering analysis, spatial surface modelling (Krigging), and the analysis of 56 statistical models for SRS and 33 for Caligus, using Information Theoretic approach to identify the supported models to explain disease occurrence.

The model outcomes for SRS found significant associations with: the number of infected sites in the barrio; the level of vaccination; fish density and smolt weight, as well as an interaction with the level of Caligus infestation. There were also significant differences between species, region and stocking season.

The Caligus model results found significant associations with fish density, salinity, degree days and variation between species and region.

The model findings were largely consistent with current SRS and Caligus understanding, and provide an excellent foundation for testing more detailed hypotheses and risk factors in the upcoming research.

A full report is being finalised, translated and will be available on the PIISAC website soon.

 

Research Platform attracts strong company interest

Recruitment of producers to the new integrated Research Platform began in earnest in January and we are delighted by the strong response.

Following a busy round of face-to-face meetings with 18 companies in January and a further 2 in March, Ausvet is very encouraged by the early response to the Research Platform.  The following companies have already agreed to participate and are well on their way to finalising data exchange arrangements with Ausvet.

                  

 

Recruitment of further companies to join this industry-owned Platform is ongoing.  The workshop held in Puerto Varas on 20 March, 2018  allowed companies to explore in depth how the Research Platform is being developed, the technology behind it and a vision for how it could be managed in the future.

In the longer term, the industry will benefit most from 100% participation in the Platform but analyses based on data from 5 to 7 companies will still allow Ausvet to demonstrate the benefits of this integrated data resource and to test the analytical model which has been developed.

The Platform will integrate complete health, management and production datasets from participating companies to support detailed epidemiological studies into the risk factors influencing SRS and Caligus across the entire industry.  Individual company data privacy and security is guaranteed to participating companies and is of paramount importance to Ausvet.  

The project team continue to encourage participation in the Research Platform.

During the visit in March, visits were made to a further 2 companies to bring the face to face company meetings to a total of twenty.

This new project website has a dynamic list of progress with company participation.

SRS post hoc model coefficients

Conditional model results
Coefficient Estimate (eb) and 95% CI Std. Error z value Pr(>|z|)
(Intercept) 0.0002 (0.0001-0.0003) 0.2004 -41.4100 < 0.0005
mod1$ncages_all_species_sc 1.0096 (0.9184-1.1098) 0.0483 0.2000 0.8433
Cumulative Degree Days 1.7517 (1.4970-2.0497) 0.0802 6.9900 0.0000
Species (Atlantic verse Coho) 0.6281 (0.4394-0.8980) 0.1824 -2.5500 0.0108
Species (Atlantic verse Rainbow Trout) 6.6260 (4.8935-8.9720) 0.1546 12.2300 < 0.0005
Initial smolt weight 1.1742 (1.0593-1.3017) 0.0526 3.0500 0.0023
Number of cages vaccinated SRS 0.8738 (0.8056-0.9478) 0.0415 -3.2500 0.0011
Number of antibiotic treated cages 1.0094 (1.0040-1.0147) 0.0027 3.4600 0.0005
Season of stocking (Autumn cf. Spring) 1.1056 (0.8513-1.4358) 0.1333 0.7500 0.4517
Season of stocking (Autumn cf. Summer) 0.8945 (0.7008-1.1415) 0.1245 -0.9000 0.3702
Season of stocking (Autumn cf. Winter) 0.7104 (0.5476-0.9216) 0.1328 -2.5700 0.0100
Number of salmonid sites within 10 km radius 1.1697 (1.05366-1.2986) 0.0534 2.9400 0.0033
Latitude 0.8579 (0.5361-1.3728) 0.2399 -0.6400 0.5228
Longitude 0.9194 (0.8028-1.0528) 0.0692 -1.2200 0.2242
Region (10 verse 11) 0.7778 (0.4568-1.3243) 0.2715 -0.9300 0.3548
Region (10 verse 12)  0.00001 (0.0000001- 0.0001)  1.1445  -9.9400  <0.0005
Zero inflated model results
(Intercept) 0.0245 (0.0157-0.0382) 0.2261 -16.4100 < 0.0005
Cumulative Degree Days  0.1505 (0.1084-0.2090)  0.1676  -11.3000  <0.0005